Facilities
R&D Laboratory
- HPLC and GC systems
- Semi-automated chromatographic purification equipment
- Semi-preparative gradient HPLC
- Cryo equipment; 2 and 5 litre reactors with minimum temperature of -80°C
- 1 isolated laboratory for special synthesis
GMP Pilot manufacturing units
- 5 independent production units
- 14 reactors from 2 to 250 litres
- 4 hydrogenation reactors
- Reactor materials: glass, glass-lined, Hastelloy C22 and zirconium
- Operation temperature: -40 °C – +200 °C
- Pressure up to 8 bars
- Centrifuge, pressure filters, grinder
Final Handling
- Class C clean room area
- 50 litres vacuum tray dryer
- 115 litres vacuum tray dryer
- 20 litres horizontal vacuum dryer
Analytical laboratory
- HPLC systems with UV/MS detectors
- GC systems with FID/MS detectors and automatic liquid/Head-Space sampler
- FT-IR spectrometer with ATR and Diffuse Reflectance accessories
- KF, acid-base and amperometric automatic titrations
- UV-spectrophotometer
- High sensitivity polarimeter
- Melting point apparatus
- TVAC / Bacterial Endotoxin tests
- NMR, MS, polymorphology studies and elemental analysis
- Stability study chambers according to ICH requirements
